Pharmaceutics – I Important Questions with Answers – Unit Wise Guide (B pharma 1st semester solved)

Pharmaceutics – I Important Questions with Answers – Unit Wise Guide (B pharma 1^st semester solved)

Section A

Unit-I Questions

1. Define prescription.
2. In which year was the most recent edition of Indian Pharmacopoeia published, and how many volumes does it contain?
3. Who is considered the father of pharmacy education in India?
4. What do the symbols Rx and signature mean in a prescription?
5. Define the term “Compendia.”
6. Outline the handling of prescriptions.
7. Define dosage forms.

Unit-II Questions

1. When can a solution be termed isotonic? (Most Important)
2. Determine 80% v/v alcohol in terms of proof spirit. (Most Important)
3. Define allegation.
4. Write the use of geometric dilution.
5. How can we calculate pediatric dose?
6. What do you understand by proof spirit? (Most Important)
7. Calculate the dose for a child of 5 years with a surface area of 1.5 m², given the adult dose is 40 mg.
8. Calculate the number of tablets prepared from 5 kg of aspirin if a tablet contains 325 mg of aspirin.

Unit-III Questions

1. Define suspension with an example.
2. Name two emulsifying agents. (Most Important)
3. Explain HLB system and Bancroft rule.
4. What is the difference between Simple Syrup IP and Simple Syrup USP?  
5. How do co-solvents improve solubility? (Most Important)
6. Define effervescent and efflorescent powders.name
7. Write the problems associated with suspensions.
8. Write the names of some emulsifiers.
9. Explain sedimentation volume. (Most Important)
10. Define elixirs.
11. Differentiate between syrups and elixirs.
12. Define physical incompatibility.

Unit-IV Questions

1. Define suppository with an example. (Most Important)
2. What do you understand by blooming of suppositories?
3. What do you mean by Displacement Value?
4. Classify bases used in suppositories.
5. What is therapeutic incompatibility? (Most Important)

Unit-V Questions

1. Classify semi-solid dosage forms. (Most Important)
2. Give examples of two ointment bases. (Most Important)
3. Name two evaluation parameters of semi-solid dosage forms.
4. Write the names of excipients used in semi-solid dosage forms.
5. Name two non-aqueous solvents used in liquid dosage forms.
6. Give any two examples of gelling agents.
7. Design the formula for Calamine lotion.
8. What are humectants? Give examples.

Section B

Unit-I Questions

1. Write a note on the history of pharmacy. (Most Important)
2. What do you understand by prescription? What are the different parts of a prescription? Draw a sample prescription.
3. Define Posology. Discuss various factors affecting posology. Calculate the doses for three children: one aged 8 years, one aged 8 months, and one weighing 15 pounds, given the adult dose of a drug is 120 mg.
4. Write a note on “Pharmacy as a career.”
5. What do you understand by Pharmacopoeia? Write a short note on IP and BP.

Unit-II Questions

1. What are the different excipients used in liquid dosage forms?
2. Describe solubility enhancement techniques.

Unit-III Questions

1. Define suspension. Discuss their method of preparation. What are the differences between deflocculated and flocculated suspensions? (Most Important)
2. Define suspension. What is flocculated and deflocculated suspension? What are the different parameters used for the evaluation of suspensions? (Most Important)
3. Illustrate the methods of preparation of emulsions, their stability problems, and methods to overcome these problems. (Most Important)
4. Define emulsions. Discuss their methods of preparation, stability problems, and methods to overcome these problems. (Most Important)

Unit-IV Questions

1. Write a descriptive note on therapeutic and physical incompatibility with examples. (Most Important)
2. Explain pharmaceutical incompatibilities in detail with examples.

Unit-V Questions

1. Classify semisolid dosage forms. What are the factors affecting dermal penetration? Discuss the method of preparation of pastes.
2. Write the method of preparation of creams.
3. Describe various methods for the preparation of ointments.
4. Discuss the mechanisms and factors influencing dermal penetration of drugs.

General/Interdisciplinary Questions

1. Write a detailed note on the history of Pharmacy in India.

Section C

Unit-I Questions

1. Write a short note on the parts of a prescription with a suitable example of a model prescription. (Most Important)
2. Define the term posology. Discuss the various factors affecting posology. (Most Important)
3. What are the different options as a career in pharmacy? (Most Important)
4. Explain the development of the profession of pharmacy in India.
5. Write the way of handling a prescription and enlist some prescription errors.

Unit-II Questions

1. Calculate the amount of 75%, 65%, 45%, and 35% alcohol that should be mixed to get 55% alcohol using the allegation method.
2. Calculate the volume of 95% alcohol required to prepare 300 ml of 70% alcohol by the allegation method. (Most Important)
3. Define Powder. Write a short note on dusting powders and effervescent powders.
4. Discuss effervescent, efflorescent, and hygroscopic powders with proper examples. (Most Important)
5. Differentiate between simple and compound powders.
6. Elaborate on dusting powders as pharmaceutical dosage forms. (Most Important)
7. How many grams of a drug are needed to make 5 liters of a 1 in 500 solution?

Unit-III Questions

1. Write a short note on gargles, mouthwashes, and throat paints with an example formula for each.
2. Define Emulsion. Describe the methods to identify instability in emulsions.
3. Describe the stability problems of suspensions and methods to overcome them.
4. Define emulsions and suspensions, and discuss the various tests to identify the type of emulsion.
5. Write the difference between flocculated and deflocculated suspensions. (Most Important)
6. Differentiate between: (i) Mouthwashes and Gargles. (ii) Lotion and Liniment.
7. Discuss various tests for the identification of emulsions. (Most Important)
8. Give the formulation and method of preparation of syrups in detail.
9. Write the method of preparation of syrups. Write the advantages and disadvantages of syrups.

Unit-IV Questions

1. Define suppositories. Explain the ideal bases for suppositories.
2. How many types of suppository bases are there? Discuss the different methods for the evaluation of suppositories.
3. Write the method of preparation and evaluation parameters of suppositories.
4. What is a gel? Discuss the methods for the evaluation of semi-solid dosage forms.
5. Discuss physical incompatibility with suitable examples. (Most Important)

Unit-V Questions

1. Classify semisolid dosage forms. What are the factors affecting dermal penetration?
2. Enlist the factors affecting dermal penetration of drugs.
3. Write a note on turpentine liniment.
4. What are the various methods of preparation of creams? (Most Important)
5. Illustrate various solubility enhancement techniques. (Most Important)
6. Discuss the various scopes of pharmacy. (Most Important)

Pharmaceutical Calculations

1. Calculate the proportions in which a manufacturing pharmacist may mix 30%, 25%, 10%, and 6% zinc oxide ointments to produce a 15% ointment.
2. A pharmacist has four batches of ointments containing 50%, 25%, 10%, and 5% drug. How many grams of each may be used to prepare 4800 g of 20% ointment?